产品编号：F215175

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	F215175
名称:	3-[(1S)-1-(2-Fluoro[1,1'-biphenyl]-4-yl)ethyl]-5-isoxazolamine
别名:	(S)-3-(1-(2-Fluoro-[1,1'-biphenyl]-4-yl)ethyl)isoxazol-5-amine
CAS号:	215175-74-9
分子式:	C₁₇H₁₅FN₂O
分子量:	282.31
种类:	Building Blocks; Miscellaneous;
应用:	3-[(1S)-1-(2-Fluoro[1,1'-biphenyl]-4-yl)ethyl]-5-isoxazolamine is an intermediate in the synthesis of Rimacalib (R505015), an inhibitor of CaMKII, inhibits VEGF expression in human acute monocytic leukemia cell and SF macrophage obtained from patient with rheumatoid arthritis. This effect may contribute to the anti-arthritic effects of Rimacalib.
参考文献	Westra, Johanna., et al.: BMC Musculoskelet Disord.,11 ,No pp. given.(2010);