产品编号：H288503
产品规格：50mg
产品价格：面议
| 标准品编号: | H288503 |
| 名称: | 2-Heptynyl Bromide |
| 别名: | 1-Bromo-2-heptyne; NSC 525137 |
| CAS号: | 18495-26-6 |
| 分子式: | C₇H₁₁Br |
| 分子量: | 175.07 |
| 种类: | Standards; Molecular Biology; Enzyme Activators and Inhibitors; |
| 应用: | 2-Heptynyl Bromide is an intermediate in the synthesis of 2-(2-Heptynylthio)phenol Acetate (H288500), which is an O-acetyl, S-alkyl thio ether of 2-thio phenol. It is a potent inhibitor of both COX-1 and COX-2, with IC50 values of 17 and 0.8uM for human recombinant COX-1 and COX-2 respectively. APHS exhibits 20-fold selectivity toward the inhibition of COX-2, yet it is still more potent than aspirin in the inhibition of COX-1. |
| 参考文献 | |
