产品编号：H288505
产品规格：25mg
产品价格：面议
| 标准品编号: | H288505 |
| 名称: | 2-(2-Heptyn-1-ylthio)phenol |
| 别名: | 2-(2-Heptyn-1-ylthio)-phenol; LM 3142 |
| CAS号: | 210350-98-4 |
| 分子式: | C₁₃H₁₆OS |
| 分子量: | 220.33 |
| 种类: | Standards; Molecular Biology; Enzyme Activators and Inhibitors; |
| 应用: | 2-(2-Heptyn-1-ylthio)phenol is an intermediate in the synthesis of 2-(2-Heptynylthio)phenol Acetate (H288500), which is an O-acetyl, S-alkyl thio ether of 2-thio phenol. It is a potent inhibitor of both COX-1 and COX-2, with IC50 values of 17 and 0.8uM for human recombinant COX-1 and COX-2 respectively. APHS exhibits 20-fold selectivity toward the inhibition of COX-2, yet it is still more potent than aspirin in the inhibition of COX-1. |
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