产品编号：H674250

产品规格：

产品价格：面议

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产品详情

标准品编号:	H674250
名称:	HX 630
别名:	4-(7,8,9,10-tetrahydro-7,7,10,10-tetramethylbenzo[b]naphtho[2,3-f][1,4]thiazepin-12-yl)benzoic Acid;
CAS号:	188844-52-2
分子式:	C₂₈H₂₇NO₂S
分子量:	441.58
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A nuclear receptor retinoid X receptor (RXR) agonist that exerts antiproliferative effects in vascular smooth muscle cells (VSMCs) in vivo and in vitro. A potential therapeutic target for vascular injury and intimal thickening. It efficiently enhanced ABCA1 mRNA expression and apoVIP(LA)I-dependent cellular cholesterol release in differentiated THP-1 cells.
参考文献	Haraguchi, G. et al.: J. Mol. Cell. Cardiol., 41, 885 (2006); Nishimaki-M. et al.: Biochem. Pharmacol., 76, 1006 (2008);