产品编号：H714825

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	H714825
名称:	N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]-acetamide
CAS号:	162361-41-3
分子式:	C₂₁H₃₅NO₄
外观:	白色固体
分子量:	365.51
溶解度:	Methanol; Dichloromethane; DMSO;
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]-acetamide is an intermediate used in the synthesis of 1-Hydroxy Fingolimod Hydrochloride (H942605), which is an impurity of the drug Fingolimond (F805000, HCl salt) which is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs.
参考文献	Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004)