产品编号：H750115

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	H750115
名称:	(E)-4-(((S)-1-((1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl)-2-((1S,3R,5S)-3-isocyano-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)amino)-4-oxobut-2-enoic Acid
别名:	Saxagliptin Impurity 6
分子式:	C₂₂H₂₇N₃O₅
分子量:	413.47
种类:	Standards; Chiral Molecules; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(E)-4-(((S)-1-((1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl)-2-((1S,3R,5S)-3-isocyano-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)amino)-4-oxobut-2-enoic Acid is an impurity of Saxagliptin (S143500). Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes.
参考文献	Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008);