产品编号：H804505

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	H804505
名称:	21β-Hydroxyeplerenone
别名:	(7α,11α,17α,21R)-9,11-Epoxy-17,21-dihydroxy-3-oxo-γ-lactone-pregn-4-ene-7,21-dicarboxylic Acid Methyl Ester;
CAS号:	1633889-97-0
分子式:	C₂₄H₃₀O₇
外观:	白色固体
熔点:	>223°C (dec.)
分子量:	430.49
溶解度:	Chloroform (Slightly), Methanol (Slightly)
种类:	Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors;
应用:	21β-Hydroxyeplerenone is a derivative of the parent compound Eplerenone (E588775), which is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
参考文献	de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),