产品编号：H804508

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	H804508
名称:	21-Hydroxyeplerenone (α, β mixture)
别名:	(7α,​11α,​17α)​-9,​11-​Epoxy-​17,​21-​dihydroxy-​3-​oxo-​γ-​lactone Methyl Ester Pregn-​4-​ene-​7,​21-​dicarboxylic Acid
CAS号:	334678-67-0
参考CAS号:	β-isomer: 1633889-97-0
分子式:	C₂₄H₃₀O₇
外观:	白色固体
熔点:	>223°C (dec.)
分子量:	430.49
储存:	冰箱, under inert atmosphere
溶解度:	Chloroform (Slightly), Methanol (Slightly)
种类:	Standards; Chiral Molecules;
应用:	21-Hydroxyeplerenone is a metabolite of Eplerenone (E588775), which is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure. 21-Hydroxyeplerenone is a metabolite of eplerenone in humans and dogs.
参考文献	de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005); Cook C., et al.: Drug Metab. Dispos., 30, 1344 (2002);