产品编号：H805180

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	H805180
名称:	(S)-1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-aminium Chloride
分子式:	C₁₄H₂₁ClN₂O₃
分子量:	300.78
种类:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(S)-1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-aminium Chloride is an intermediate used in the synthesis of (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2yl]pyrazine-2-carboxamide (H805105), which is an impurity of bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
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