产品编号：H953640

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	H953640
名称:	1-(3-Hydroxybutan-2-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one
别名:	2,4-Dihydro-2-(2-hydroxy-1-methylpropyl)-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one
CAS号:	125272-25-5
分子式:	C₂₂H₂₇N₅O₃
分子量:	409.48
种类:	Building Blocks; Miscellaneous;
应用:	1-(3-Hydroxybutan-2-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one is an intermediate in the synthesis of Itraconazole (I937500), An orally active antimycotic structurally related to Ketoconazole; an antifungal agent.
参考文献	Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984); Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989); Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993)