产品编号：H977590

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	H977590
名称:	3-Hydroxy-3,3',5'-triiodo-thyroxine (Mixture of Diastereomers)
别名:	2-Amino-3-hydroxy-3-(4-(4-hydroxy-3,5-diodophenoxy)-3-iodophenyl)propanioc Acid; Beta-Hydroxy T3 Impurity;
分子式:	C₁₅H₁₂I₃NO₅
分子量:	666.97
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-Hydroxy-3,3',5'-triiodo-thyroxine (Mixture of Diastereomers) is a derivative compound of Thyroxine (H97750). Thyroxine is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
参考文献	Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976), Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988), Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996), Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997),