产品编号：I140085

产品规格：10g

产品价格：面议

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产品详情

标准品编号:	I140085
名称:	(±)-Ibuprofen Methyl Ester
别名:	2-(4-Isobutylphenyl)propionic Acid Methyl Ester; Ibuprofen Methyl Ester; Methyl 2-(4-Isobutylphenyl)propionate; Methyl 2-(4'-Isobutylphenyl)propanoate; Methyl 2-(p-Isobutylphenyl)propionate; Methyl α-(4-Isobutylphenyl)propionate; Methyl α-(p-Isobutylphenyl)propionate; Racemic ibuprofen Methyl Ester
CAS号:	61566-34-5
分子式:	C₁₄H₂₀O₂
外观:	Clear Colourless Oil
熔点:	N/A
分子量:	220.31
储存:	冰箱
溶解度:	Chloroform (Slightly), Ethyl Acetate (Slightly)
种类:	Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(±)-Ibuprofen Methyl Ester is a phototoxic, photoproduct of Ibuprofen (I140000), a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Ibuprofen is also used as an anti-inflammatory drug.
参考文献	Miranda, M.A., et. al.: Toxicol. In Vitro, 5, 451 (1991); Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)

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