产品编号：I400155

产品规格：5g

产品价格：面议

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产品详情

标准品编号:	I400155
名称:	Ibuprofen Sodium Salt Dihydrate
别名:	2-(4-Isobutylphenyl)propionic Acid Sodium Salt; Ibuprofen Sodium; Sodium 2-(4-isobutylphenyl)propionate; Sodium Ibuprofen; α-Methyl-4-(2-methylpropyl)benzeneacetic Acid Sodium Salt
CAS号:	527688-20-6
参考CAS号:	Free form 15687-27-1 , Na Salt: 31121-93-4
分子式:	C₁₃H₁₇NaO₂ •2(H₂O)
外观:	白色固体
熔点:	>100°C (dec.)
分子量:	228.2621802
储存:	-20°C Freezer
溶解度:	Methanol (Slightly), Water (Slightly)
种类:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Ibuprofen Sodium Salt is a sodium salt of Ibuprofen (I140000), a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Ibuprofen has has been shown to reduce Ebola infection in rodents (4).This compound is a contaminant of emerging concern (CECs).
参考文献	Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); (4) Chem. and Eng. News p9, July 4 (2016); Mandal, P., et al.: Dalton Trans., 47, 517 (2018)