产品编号：I822210

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	I822210
名称:	n-Propyl (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoate
别名:	(2E)​-2-Ccyano-​3-​(3,​4-​dihydroxy-​5-​nitrophenyl)​-​2-​propenoic Acid Propyl Ester; Entacapone EP Impurity I
CAS号:	1364322-42-8
分子式:	C₁₃H₁₂N₂O₆
分子量:	292.24
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Isopropyl (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoate is an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
参考文献	Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),