产品编号：K139700

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	K139700
名称:	Karacoline
别名:	Karakoline; 11aH-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-1,8,14-triol deriv.; Carmichaeline; (1α,14α,16β)-20-Ethyl-16-methoxy-4-methylaconitane-1,8,14-triol; (1α,​14α,​16β)​-20-​Ethyl-​16-​methoxy-​4-​methyl-​aconitane-​1,​8,​14-​triol;
CAS号:	39089-30-0
分子式:	C₂₂H₃₅NO₄
分子量:	377.52
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Karacoline is an Aconitane (A189875) derivative, which is a neurotoxin which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction.
参考文献	Derbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010), Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010),