产品编号：K186017

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	K186017
名称:	(2R,4R)-trans-Ketoconazole-d8
别名:	1-Acetyl-4-[4-[[(2R,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine-d8; (2R-trans)-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine-d8; Ketoconazole Impurity C-d8
参考CAS号:	Unlabelled: 142128-58-3
分子式:	C₂₆H₂₀D₈Cl₂N₄O₄
分子量:	539.48
种类:	Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(2R,4R)-trans-Ketoconazole-d8 is the isotope labelled analog of (2R,4R)-trans-Ketoconazole (K186015); an isomer of Ketoconazole (K186000). Ketoconazole inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. It has antimetastatic and antineoplastic activity and is an orally active 5-lipoxygenase and thromboxane synthase inhibitor.
危险品:	Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
参考文献	Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986); Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989); Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988); Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)