KL001

我要购买

产品编号:K571200

产品规格:10mg

产品价格:面议


产品详情

标准品编号: K571200
名称: KL001
别名: N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)-methanesulfonamide
CAS号: 309928-48-1
分子式: C₂₁H₂₂N₂O₄S
分子量: 398.48
种类: Research Tools;
应用: KL001 is a small molecule that specifically interacts with cryptochrome (CRY). KL001 prevented ubiquitin-dependent degrdation of CRY, resulting in lengthening of the circadian period. KL001-mediated CRY stabilization inhibited glucagon-induced gluconeogenesis in primary hepatocytes making it a tool to study the regulation of CRY-dependent physiology and aid development of clock-based therapeutics of diabetes.
参考文献