产品编号：M260502
产品规格：10mg
产品价格：面议
| 标准品编号: | M260502 |
| 名称: | L-Methionine [R,S]-Sulfoximine-13C5 |
| 别名: | L-S-[3-Amino-3-carboxypropyl]-S-methyl-[R,S]-sulfoximine-13C5; (2S)-2-Amino-4-(S-methylsulfonimidoyl)butanoic Acid-13C5; |
| 参考CAS号: | 15985-39-4 unlabelled |
| 分子式: | ¹³C₅H₁₂N₂O₃S |
| 外观: | 白色固体 |
| 熔点: | >190°C (dec.) |
| 分子量: | 185.19 |
| 储存: | -20°C Freezer |
| 溶解度: | Water (Slightly) |
| 种类: | Research Tools; Amino Acids; Isotopic Labeled Analogues; |
| 应用: | L-Methionine [R,S]-Sulfoximine-13C5,15N is the isotope labelled analog of L-Methionine [R,S]-Sulfoximine. Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM). Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease. |
| 参考文献 | |
