产品编号：M331425

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	M331425
名称:	2-​[4-​[(Methylsulfonyl)​amino]​phenoxy]​-​acetic Acid Methyl Ester
别名:	Methyl 2-(4-(Methylsulfonamido)phenoxy)acetate
CAS号:	1192366-04-3
分子式:	C₁₀H₁₃NO₅S
外观:	Pink Powder
分子量:	259.28
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-​[4-​[(Methylsulfonyl)​amino]​phenoxy]​-​acetic Acid Methyl Ester is an intermediate in the synthesis of 2-(4-(Methylsulfonamido)phenoxy)acetic Acid (M332215). 2-(4-(Methylsulfonamido)phenoxy)acetic Acid is a metabolite of antiarrhythmic drug Dofetilide (D525700), which is a is a potassium channel blocker.
参考文献	Smith, D., et al.: Xenobiotica, 22, 709 (1992); Carmeliet, D., et al.: J. Pharmacol. Exp. Ther., 262, 809 (1992); Walker, D., et al.: Drug Metab. Dispos., 24, 447 (1996); Norgaard, B.L., et al.: Am. Heart J., 137, 1062 (1999); Torp-Pedersen, C., et al.: N. Engl. J. Med. 341, 857 (1999)