产品编号：M425300

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	M425300
名称:	ML-213
别名:	N-(2,4,6-Trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamide;
CAS号:	489402-47-3
分子式:	C₁₇H₂₃NO
分子量:	257.37
种类:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	ML-213 is a selective KV7.2 (KCNQ2) and KV7.4 (KCNQ4) channel opener (EC50 values are 230 and 510 nM for KV7.2 and KV7.4 respectively). ML-213 displays >80-fold selectivity against KV7.1, KV7.3 and KV7.5 in a thallium-based fluorescence assay.
参考文献	Rundfeldt, C., et al.: Eur. J. Pharmacol., 336, 243 (1997); Singh, N., et al.: Brain, 126, 2726 (2003); Munro, G., et al.: J. Med. Chem., 50, 2576 (2007); Qi, J., et al.: Eur. J. Med. Chem., 46, 934 (2011);