产品编号：M897550

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	M897550
名称:	2-Methyl-4-((3aS,4S,6S)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-2-ol
分子式:	C₁₅H₂₇BO₃
外观:	Pale Yellow Oil
分子量:	266.18
溶解度:	Dichloromethane; Ethyl Acetate; Methanol
种类:	Building Blocks; Chiral Molecules;
应用:	2-Methyl-4-((3aS,4S,6S)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-2-ol is an intermediate for the synthesis of 3-Hydroxy Bortezomib (H818150), which is a metabolite of Bortezomib (B675700); the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.
参考文献	Nawrocki, S.T., et al.: Cancer Res., 65, 11510 (2005); Drahl, C.: Chem. and Eng. News, 87, 41 (2009)