产品编号：N925280

产品规格：5mg

产品价格：面议

---

产品详情

标准品编号:	N925280
名称:	NU6027
别名:	6-(Cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine; 2,6-Diamino-4-(cyclohexylmethoxy)-5-nitrosopyrimidine; 6-(Cyclohexylmethoxy)-5-nitroso-2,4-pyrimidinediamine
CAS号:	220036-08-8
分子式:	C₁₁H₁₇N₅O₂
分子量:	251.28
类别:	Research Tools;
应用:	NU6027 is a potent cyclin-dependent kinase (CDK) and Rad3-related kinase (ATR) inhibitor. NU6027 has been shown to inhibit tumor cell growth. NU6027 inhibits ATR, impairing G2/M arrest and homologous recombination thus increasing sensitivity to DNVIP(LA)damaging agents and poly(ADP-ribose) polymerase (PARP) inhibitors
参考文献	Arris, C.E., et. al.: J. Med. Che., 43, 2797 (2000); Peasland, A., et. al.: Brit. J. Cancer, 105, 372 (2011)