产品编号：O712500

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	O712500
名称:	Otamixaban
别名:	(αR)-3-(Aminoiminomethyl)-α-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]ethyl]benzenepropanoic Acid Methyl Ester; [R-(R*,R*)]-3-(Aminoiminomethyl)-α-[1-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]ethyl]benzenepropanoic Acid Methyl Ester; FXV 673; Methyl (2R,3R)-2-[3-Amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate;
CAS号:	193153-04-7
分子式:	C₂₅H₂₆N₄O₄
分子量:	446.5
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. Clinical studies show that it is efficacious, safe and well tolerated in humans and therefore has considerable potential for the treatment of acute coronary syndrome.
参考文献	Guertin, K.R. et al.: Curr. Med. Chem., 14, 2471 (2007); Hinder, M. et al.: Clin. Pharmacol. Therap., 80, 691 (2006); Hinder, M. et al.: Thromb. Haemost., 95, 224 (2006);