产品编号：O855310

产品规格：500 mg

产品价格：面议

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产品详情

标准品编号:	O855310
名称:	2-Oxo-2,3-dihydrobenzimidazole-1-carboxylic Acid tert-Butyl Ester
别名:	tert-Butyl 2-Oxo-2,3-dihydro-1H-benzimidazole-1-carboxylate; 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxylic Acid 1,1-Dimethylethyl Ester
CAS号:	161468-45-7
分子式:	C₁₂H₁₄N₂O₃
外观:	白色固体
分子量:	234.25
溶解度:	DÇM, Ethyl Acetate
类别:	Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	2-Oxo-2,3-dihydrobenzimidazole-1-carboxylic Acid tert-Butyl Ester is an substituent in the synthesis of Domperidone (D531100), a novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier and is used as an anti-emetic agent.
参考文献	Badarau, E., et al.: J. Enzyme. Inhib. Med. Chem., 25, 301 (2010); Guichard, G., et al.: J. Org. Chem., 64. 8702 (1999);