产品编号：P294103

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	P294103
名称:	PF-06291874
别名:	N-[4-[(1S)-1-[3,5-Dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy]butyl]benzoyl]-β-alanine; Glucagon Receptor Antagonists-4
CAS号:	1393124-08-7
分子式:	C₂₆H₂₈F₃N₃O₄
分子量:	503.51
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	PF-06291874 is a novel and potent glucagon receptor antagonist for the potential treatment of diabetes mellitus. PF-06291874, has a lower molcular weight and lipophilicity than historical glucagon receptor antagonists, resulting in excellent selectivity in broad-panel screening, lower cytotoxicity, and excellent overall in vivo safety in early pre-clinical testing.
参考文献	Guzman-Perez, Angel., et al.: Bioorganic Med. Chem. Lett., Â23,Â3051 (2013);