产品编号：P552505

产品规格：2.5mg

产品价格：面议

---

产品详情

标准品编号:	P552505
名称:	Pixantrone-N7-desethanamine Dihydrochloride
别名:	N7-(Desaminoethyl)-Pixantrone Dihydrochloride; 6-Amino-9-[(2-aminoethyl)amino]-benz[g]isoquinoline-5,10-dione Dihydrochloride
参考CAS号:	free base: 1430561-04-8
分子式:	C₁₅H₁₄N₄O₂
分子量:	282.3
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Pixantrone-N7-desethanamine Dihydrochloride is an impurity of Pixantrone (P552500), an antineoplastic drug belonging to group of antitumor antibiotics. Pixantrone is an anlogue of Mitoxantrone (M373425) and is just as potent in the treatment of multiple sclerosis with fewer toxic effects on cardiac tissue. Studies suggest that Pixantrone significantly reduces amyloid beta (A beta(1-42)) neurotoxicity, a mechanism implicated in Alzheimer's disease.
参考文献	Cavalletti, E. et al.: Invest. New Drugs, 25, 187 (2007); Gonsette, R.E. et al.: J. Neurol. Sci., 223, 81 (2004); Colombo, R. et al.: Electrophoresis, 30, 1418 (2009)