产品编号：P688207

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	P688207
名称:	Pomalidomide-d2
别名:	4-Amino-2-(2,6-dioxo-3-piperidinyl)isoindole-1,3-dione-d2; 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione-d2; Actimid-d2; CC 4047-d2; IMiD 3-d2
参考CAS号:	19171-19-8
分子式:	C₁₃H₉D₂N₃O₄
外观:	Bright Yellow Solid
分子量:	275.26
溶解度:	DMF
类别:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Pomalidomide-d2 is an intermediate for the synthesis of Pomalidomide-(d4 major) (P688202), which is the labeled analogue of Pomalidomide (P688200), a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
参考文献	Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)