产品编号：R060000

产品规格：2mg

产品价格：面议

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产品详情

标准品编号:	R060000
名称:	R406
别名:	6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one Monobenzenesulfonate; Tamatinib;
CAS号:	841290-81-1
参考CAS号:	841290-80-0 free base
分子式:	C₂₂H₂₃FN₆O₅ • ( C₆H₆O₃S)
外观:	白色至Light Grey Solid
熔点:	182-184°C
分子量:	470.4515818
储存:	冰箱
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	R406 is a potent Syk inhibitor which affects Dectin-1-mediated signalling in mammilian cells. R406 thus acts an anti-fungal agent. Also a potential anti-leukemia agent, through modulation of sphingosine-1 phosphate receptor 1 (S1PR1).
参考文献	Borge, M. et al.: J. Immunol., 193, 3165 (2014); Kimura, Y. et al.: J. Biol. Chem., 289, 31565 (2014);