产品编号：R143325

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	R143325
名称:	Regorafenib N-β-D-Glucuronide (Pyridine)-N-oxide
别名:	4-(4-(3-((2R,3R,4S,5S,6S)-6-Carboxy-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)-3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-2-(methylcarbamoyl)pyridine 1-Oxide
分子式:	C₂₇H₂₃ClF₄N₄O₁₀
分子量:	674.94
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Regorafenib N-β-D-Glucuronide (Pyridine)-N-oxide is a derivative of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent.
参考文献	Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)