产品编号：R535025

产品规格：0.5mg

产品价格：面议

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产品详情

标准品编号:	R535025
名称:	ent-Ritonavir
分子式:	C₃₇H₄₈N₆O₅S₂
分子量:	720.94
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	ent-Ritonavir is derived from D-Valine Methyl Ester Hydrochloride (V094335), which is a protected form of D-Valine (V094200). D-Valine (an isomer of the essential amino acid L-Valine [V094205])exhibited inhibitory effects on fibroblasts that contaminated mammalian kidney cultures, allowing for selective growth epithelial cells. D-Valine is also known for its presence in the structure of Actinomycin D, an antitumour drug. D-Valine is naturally synthesized by Streptomyces antibioticus.
参考文献	Chu, W., et al.: J. Am. Chem. Soc., 116, 7971 (1994); Gilbert, S & Migeon, B.: J. Cell. Phys., 92, 161 (1977); Salzman, L., et al.: J. Biol. Chem., 239, 1864 (1964); Sordillo, L., et al.: Cell Biol. Int. Rep., 12, 355 (1988)