产品编号：R701112

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	R701112
名称:	RTI-113-d5
别名:	(1R,2S,3S,5S)-3-(4-Chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Phenyl Ester-d5 Hydrochloride; [1R-(exo,exo)]-3-(4-Chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Phenyl Ester-d5 Hydrochloride; RTI 113-d5; RTI 4229-113-d5;
参考CAS号:	类似: 141807-57-0
分子式:	C₂₁H₁₈D₅Cl₂NO₂
分子量:	397.35
类别:	Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Labelled RTI-113. RTI-113 is a 3-phenyltropane analogue that acts as a potent and selective dopamine uptake inhibitor. RTI-113 has been shown to reduce cocaine self-administration at high occupancy of dopamine transporter. Studies suggest that RTI-113 and its analogs may be useful tools for developing potential agonist therapies for cocaine dependence.
参考文献	Dworkin, S. et al.: Synapse, 30, 49 (1998); Negus, S.S. et al.: Pharmacol. Biochem. Behav., 91, 333 (2009); Cook, C. et al.: Eur. J. Pharmacol., 442, 93 (2002);