产品编号：R701527

产品规格：

产品价格：面议

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产品详情

标准品编号:	R701527
名称:	Ruboxistaurin-d6 Hydrochloride
别名:	(9S)-9-[[(Dimethyl-d6)amino]methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-Dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione Hydrochloride; LY 333531-d6;
CAS号:	1794767-04-6
参考CAS号:	类似: 169939-93-9
分子式:	C₂₈H₂₃D₆ClN₄O₃
分子量:	511.04
类别:	Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Labelled Ruboxistaurin. Ruboxistaurin is a protein kinase C (PKC) β inhibitor, exhibits significant anti-angiogenic activity that reduces the response of vascular endothelial cells to stimulation by vascular endothelial growth factor (VEGF). Ruboxistaurin is used in treatment of diabetic microvascular complications.
参考文献	Miller, J. et al.: Diabetes Metab. Rev., 13, 37 (1997); Suzuma, I. et al.: J. Biol. Chem., 277, 1047 (2002),;Ali, N. et al.: J. Pharmacol. Sci., 98, 130 (2005);