产品编号：R702000

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	R702000
名称:	(R)-Ruxolitinib (>90%)
别名:	(βR)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile; INCB 018424;
CAS号:	941678-49-5
分子式:	C₁₇H₁₈N₆
外观:	白色至Beige Solid
熔点:	84-89°C
分子量:	306.36
储存:	-20˚C Freezer
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis. Potent JAK2 inhibitor.
参考文献	Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);

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