产品编号：S080935

产品规格：1mg

产品价格：面议

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产品详情

标准品编号:	S080935
名称:	(2R,4S)-Sacubitril-O-isobutane
别名:	[S-(R*,S*)]-γ-[[4-(1,1-Dimethylethoxy)-1,4-dioxobutyl]amino]-α-methyl-1,1'-biphenyl]-4-pentanoic Acid Ethyl Ester; (2R,4S)-Ethyl 5-([1,1'-Biphenyl]-4-yl)-4-(4-(tert-butoxy)-4-oxobutanamido)-2-methylpentanoate
CAS号:	149709-64-8
分子式:	C₂₈H₃₇NO₅
外观:	Yellowish Oil
分子量:	467.6
储存:	-20°C Freezer
溶解度:	Alcohols, Dichloromethane
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(2R,4S)-Sacubitril-O-isobutane is an intermediate in the synthesis of (2S,4S)-Sacubitril (S080915). (2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.
参考文献	McMurray, J., et al.: N. Eng. J. Med., 371 (2014)