产品编号：S083600

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	S083600
名称:	SAG
别名:	3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]- benzo[b]thiophene-2-carboxamide;
CAS号:	912545-86-9
分子式:	C₂₈H₂₈ClN₃OS
外观:	Orange to Red Oil
分子量:	490.06
储存:	-20°C Freezer
溶解度:	Water
稳定性:	Light Sensitive
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A potent agonist of Hedgehog (Hh) signalling by activating the Smoothened (Smo) protein function. Studies identify novel properties of molecules displaying potential interest in the treatment of various cancers and brain diseases, and demonstrate that Smo is capable of signaling through G15.
参考文献	DeCamp, D., et al.: J. Biol. Chem., 275, 26322 (2000), Ahn, S., et al.: Nature, 437, 894 (2005), Huangfu, D., et al.: Development, 133, 3 (2006), Loulier, K., et al.: J. Neurochem., 98, 530 (2006),