产品编号：S154705

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	S154705
名称:	SBI-0206965
别名:	2-((5-Bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide
分子式:	C₂₁H₂₁BrN₄O₅
分子量:	489.32
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	SBI-0206965 is an inhibitor of ULK1. It also blocks ULK1-dependent cell survival following nutrient deprivation. ULK1 is a serine/threonine kinase that acts upstream of phosphatidylinositol 3-kinase (PI3K) to regulate the formation of autophagophores, the precursors of autophagosomes, in response to nutrient deprivation.
参考文献	Egan, D.F., et al.: Mol. Cell 59, 285 (2015).