产品编号：S565005

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	S565005
名称:	SMCC-DM1
别名:	N2'-deacetyl-N2'-[3-[[1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine; DM1 SMCC;
CAS号:	1228105-51-8
分子式:	C₅₁H₆₆ClN₅O₁₆S
外观:	白色至白色固体
熔点:	>166°C (dec.)
分子量:	1072.61
储存:	-20°C Freezer
溶解度:	Chloroform (Slightly), Methanol (Slightly)
类别:	Standards; Antibodies; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	SMCC-DM1 is a mertansine drug (DM1) with a reactive linker SMCC to make antibody drug conjugate. DM1 (mertansine), a thiol-containing maytansinoid, is a potent microtubule-disrupting agent.
参考文献	Lambert JM., et al.: J Med Chem.,57, 6949 (2014); Luo, Quanzhou., et al.: Anal. Chem., 88, 695Â(2016);