产品编号：S139510
产品规格：25mg
产品价格：面议
| 标准品编号: | S139510 |
| 名称: | SAR131675 |
| 别名: | 2-Amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide; 2-Amino-1-ethyl-1,4-dihydro-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide |
| CAS号: | 1092538-80-1 |
| 分子式: | C₁₈H₂₂N₄O₄ |
| 外观: | 白色至淡黄色固体 |
| 熔点: | >206°C (dec.) |
| 分子量: | 358.39 |
| 储存: | 冰箱 |
| 溶解度: | Chloroform (Slightly), DMSO (Slightly) |
| 类别: | Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells. SAR131675 also dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD. |
| 参考文献 | |
