产品编号：S676720

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	S676720
名称:	(1R,3S)-Solifenacin Hydrochloride
别名:	(1R)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3S)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochloride;
CAS号:	180468-40-0
参考CAS号:	774517-20-3 - Free base1262506-09-1 - Succinate s
分子式:	C₂₃H₂₇ClN₂O₂
外观:	白色至淡黄色固体
熔点:	>124°C (dec.)
分子量:	398.93
储存:	Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:	DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
类别:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(1R,3S-)Solifenacin Hydrochloride is an optical isomer of Solifenacin Hydrochloride (S676700), a muscarinic M3 receptor antagoinst. Used in treatment of urinary incontinence.
参考文献	Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002), Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004), Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004), Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005), Habb, F., et al.: Eur. Urol. 47, 376 (2005), Payne, C.K., et al.: Drugs, 66, 175 (2006); Naito, R. et al.: J. Med. Chem., 48, 6597 (2005);