产品编号：S676800

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	S676800
名称:	Sonepiprazole Mesylate
别名:	4-[4-[2-[(1S)-3,4-Dihydro-1H-2-benzopyran-1-yl]ethyl]-1-piperazinyl]benzenesulfonamide Methanesulfonate; PNU 101387G; (S)-4-[4-[2-(3,4-Dihydro-1H-2-benzopyran-1-yl)ethyl]-1-piperazinyl]benzenesulfonamide Monomethanesulfonate; 4-[4-[2-[(1S)-3,4-Dihydro-1H-2-benzopyran-1-yl]ethyl]-1-piperazinyl]benzenesulfonamide Monomethanesulfonate; Sonepiperazole Mesylate; U 101387G
CAS号:	170858-34-1
参考CAS号:	Free base: 170858-33-0
分子式:	C₂₁H₂₇N₃O₃S ( CH₄O₃S)
外观:	白色至白色固体
熔点:	>212°C (dec.)
分子量:	401.529611
储存:	冰箱
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A selective D4 dopamine antagonist that exhibits low affinity at other monoamine receptors (Ki > 2000 nM). Induces c-fos gene expression in medial prefrontal cortex in a similar manner to Clozapine (C587500).
参考文献	Merchant, K.M. et al.: J. Pharm. Exp. Ther., 279, 1392 (1996); Rubinstein, M. et al.: J. Neurosci., 21, 3756 (2001); Marona-Lewicka, D. et al.: Behav. Pharmacol., 20, 114 (2009);