产品编号：S684538

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	S684538
名称:	SR-3029
别名:	N-[(6,7-Difluoro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-(4-morpholinyl)-9H-purin-6-amine; SR 3029
CAS号:	1454585-06-8
分子式:	C₂₃H₁₉F₃N₈O
分子量:	480.45
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	SR-3029 is a potent and selective CK1δ and CK1ε inhibitor (IC50 values are 44 and 260 nM, respectively). Exhibits selectivity for CK1δ and CK1ε over a panel of other kinases. Inhibits proliferation of melanoma and breast cancer cell lines in vitro. Also inhibits growth of breast tumor xenografts in mice.
参考文献	Bibian, Mathieu., et al.: Bioorg Med Chem Lett., 23,Â4374Â(2013); Rosenberg, L. H.,et al.: Sci Transl Med., 7, 318ra202 (2015)