产品编号：S688750

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	S688750
名称:	Suberoyl Bis-hydroxamic Acid
别名:	N1,N8-Dihydroxyoctanediamide; N,N'-Dihydroxyoctanediamide; SBHA; Suberodihydroxamic Acid; Suberic Bishydroxamate;
CAS号:	38937-66-5
分子式:	C₈H₁₆N₂O₄
外观:	白色至Light Beige Solid
熔点:	154-156°C
分子量:	204.22
储存:	Hygroscopic, 冰箱, under inert atmosphere
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Histone deacetylase inhibitor. A cell-permeable inhibitor of HDAC1 and HDAC3. Shown to suppresses the growth of proliferating keratinocytes and squamous cell carcinoma cells.
参考文献	Marks, P.A., et al.: Proc.Natl. acad. Sci., 91, 10251 (1994), Brinkmann, H., et al.: J. Biol. Chem., 276, 22491 (2001), Haupt, S., et al.: J. Cell Sci., 116, 4077 (2003), Zhang, X., et al.: Biochem. Pharmacol., 66, 1537 (2003), Crighton, D., et al.: Biochim. Biophys Acta, 1705, 3 (2004),