产品编号：S699220
产品规格：10mg
产品价格：面议
| 标准品编号: | S699220 |
| 名称: | Sulindac Sulfide |
| 别名: | (Z)-5-Fluoro-2-methyl-1-[p-(methylthio)benzylidene]indene-3-acetic Acid; Sulindac Related Compound C |
| CAS号: | 49627-27-2 |
| 参考CAS号: | EZ undefined: 32004-67-4 |
| 分子式: | C₂₀H₁₇FO₂S |
| 外观: | Yellow to Orange Solid |
| 熔点: | 177-182°C |
| 分子量: | 340.41 |
| 储存: | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| 溶解度: | DMSO (Slightly), Methanol (Very Slightly, Heated) |
| 稳定性: | Hygroscopic |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP. |
| 参考文献 | |
