产品编号：S870002

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	S870002
名称:	Suvorexant-d6
别名:	[(7R)-4-(5-Chloro-2-benzoxazolyl)hexahydro-7-methyl-1H-1,4-diazepin-1-yl][5-methyl-d3-2-(2H-1,2,3-triazol-2-yl)phenyl-d3]-methanone;5-Chloro-2-[(5R)-5-methyl-4-[5-methyl-d3-2-(2H-1,2,3-triazol-2-yl)benzoyl-d3]-1,4-diazepan-1-yl]-1,3-benzoxazole; MK 4305-d6; [(R)-4-(5-Chloro-benzooxazol-2-yl)-7-methyl-[1,4]diazepan-1-yl]-(5-methyl-d3-2-[1,2,3]triazol-2-yl-phenyl-d3)-methanone
参考CAS号:	类似: 1030377-33-3
分子式:	C₂₃H₁₇D₆ClN₆O₂
分子量:	456.96
类别:	Building Blocks; Isotopic Labeled Analogues;
应用:	Suvorexant-d6 is the labeled analog of Suvorexant (S870000), a dual (non-selective) orexin receptor antagonist in development by Merck & Co. for the treatment of insomnia. It works by turning off wakefulness rather than by inducing sleep. Users of higher doses had an increased rate of suicidal ideation.
参考文献	Cox, C., et al.: J. Med. Chem., 53, 5320 (2010); Baxter, C., et al.: Org. Process Res. Dev., 15, 367 (2011); Winrow, C., et al.: J. Neurogenet., 25, 52 (2011); Mieda, M., et al.: CNS Drugs, 27, 83 (2013); Osborne, R.: Nat. Rev. Drug Discov., 12, 492 (2013)