产品编号：T004942
产品规格：10mg
产品价格：面议
| 标准品编号: | T004942 |
| 名称: | TAK-960-d3 |
| 别名: | 4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)benzamide-d3; |
| 参考CAS号: | Unlabelled: 1137868-52-0 |
| 分子式: | CH₃₁D₃F₃N₇O₃ |
| 分子量: | 564.62 |
| 类别: | Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Isotope labelled TAK-960 is a potent and selective inhibitor of polo-like kinase 1 (PLK1), a serine/threonine protein kinase involved in key processes during mitosis. TAK-960 has shown activity in several tumor cell lines, including those that express multidrug-resistant protein 1 (MDR1). TAK-960 treatments has shown significant efficacy against multiple tumor xenografts and is a potential chemotherapeutic agent for patients with advanced tumors. |
| 参考文献 | |
