产品编号：T007240

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	T007240
名称:	(1R,2S)-Tapentadol-(3-oxo-O-methyl)
别名:	(αS,βR)-β-Ethyl-3-methoxy-N,N,α-trimethyl-benzenepropanamide; (2S,3R)-3-(3-Methoxyphenyl)-N,N,2-trimethylpentanamide;
CAS号:	1313429-39-8
分子式:	C₁₅H₂₃NO₂
外观:	Reddish Yellow Oil
分子量:	249.35
储存:	Room Temperature
溶解度:	Dichloromethane, DMSO, Methanol
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(1R,2S)-Tapentadol-(3-oxo-O-methyl) is an intermediate in the synthesis of (1R,2S)-Tapentadol Hydrochloride (T007230). (1R,2S)-Tapentadol is the (1R,2S)-isomer of Tapentadol (T007200, HCl), a novel, centrally acting oral analgesic with a dual mode of action that has demonstrated efficacy in preclinical and clinical models of pain relief.
参考文献	Znaleziona, J., et al.: J. Pharmaceut. Biomed., 105, 10 (2015); Boxenbaum, H., et al.: J. Pharm. Sci., 2, 47 (1999); Boase, S., et al.: Br. J. Clin. Pharmacol., 54, 493 (2002); Armstrong, S., et al.: Psychosomatics, 44, 515 (2003); Bjornsson, T., et al.: Drug Metab. Dispos., 31, 815 ( 2003)