产品编号：T222810

产品规格：10mg

产品价格：面议

---

产品详情

标准品编号:	T222810
名称:	7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline 1-oxide
别名:	Varenicline-N-oxide
CAS号:	2306217-12-7
分子式:	C₁₃H₁₃N₃O
分子量:	227.26
类别:	Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Varenicline-N-oxide is an impurity of Varenicline (V098492), a nicotinic α4β2 acetylcholine receptor partial agonist identified for smoking cessation.
参考文献	Lu, Y., et. al.: J. Pharm. Biomed. Anal., 155, 306 (2018)Benowitz, N., et al.: Clin. Pharmacol. Ther., 44, 23 (1988);Cohen, C., et al.: J. Pharmacol. Exp. Ther., 306, 407 (2003);Tapper, A., et al.: Science, 306, 1029 (2004);Coe, J., et al.: J. Med. Chem., 48, 3474 (2005);Obach, R., et al.: Drug Metab. Disp., 34, 121 (2006)