产品编号：T367005

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	T367005
名称:	Thiomuscimol Biotin
别名:	Thiomuscimol-d-Biotin; Thiomuscimol-(3aS,​4S,​6aR)​-Hexahydro-​2-​oxo-​1H-​Thieno[3,​4-​d]​imidazole-​4-​pentanoic Acid, Thiomuscimol Meribin; Thiomuscimol Medebiotin; Thiomuscimol D(+)-Biotin
分子式:	C₁₄H₂₀N₄O₃S₂
分子量:	356.46
类别:	Research Tools; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Thiomuscimol (62020-54-6 #CAS) conjugated with Biotin (B389040 #CAS). This is a useful compound for research and organic synthesis. Biotin is a growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides. The richest sources are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue. On the other hand, Thiomuscimol has a photoaffinity label for the GABAA receptor. Thiomuscimol inhibits [3H]muscimol binding to brain GABAA receptors.
参考文献	Lykkeberg, J., et al.: Acta Chem. Scand., B, 30, 781 (1976), Bureau, M.H., et al.: J. Neurochem., 61, 1479 (1993), N'Goka, V;., et al.: J. Med. Chem., 34, 2547 (1991); du Vigneaud, et al.: J. Biol. Chem., 146, 475 (1942); Traub, et al.: Nature, 178, 649 (1956); Siegel, H., et al.: Experienta, 37, 789 (1981); Vesely, D.L., Science, 216, 1329 (1982); Hugues, M., et al.: Biochemistry, 31, 12 (1992);