产品编号：T444695
产品规格：2.5mg
产品价格：面议
| 标准品编号: | T444695 |
| 名称: | Timosaponin A3 |
| 别名: | (3β,5β,25S)-Spirostan-3-yl 2-O-β-D-glucopyranosyl-β-D-galactopyranoside; Anemarsaponin A 3; Filiferin B; Sarsasapogenin, 2-O-β-D-glucopyranosyl-β-D-galactopyranoside; Xilingsaponin A; Zhi-mu saponin |
| CAS号: | 41059-79-4 |
| 分子式: | C₃₉H₆₄O₁₃ |
| 分子量: | 740.92 |
| 类别: | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Steroids; |
| 应用: | Timosaponin A3 suppresses certain human tumor processes and has the potential to be developed as an anticancer agent. Reverses multi-drug resistance in human chronic myelogenous leukemia K562/ADM cells via downregulation of MDR1 and MRP1 expression by inhibiting PI3K/Akt signaling pathway. Induction of mitochondrial-dependent apoptosis in HepG2 human hepatocellular carcinoma cells. Timosaponin A3 is a potent inhibitor of U46619, that induces rat platelet aggregation and exhibited superior selectivity for the TP receptor vs. other G protein-coupled receptors and a PKC activator. |
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