产品编号：T895945

产品规格：50mg

产品价格：面议

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产品详情

标准品编号:	T895945
名称:	(-)-N-Trifluoroacetyl-1-aminoindan
别名:	N-[(1R)-2,3-Dihydro-1H-inden-1-yl]-2,2,2-trifluoro-acetamide; (R)-N-(2,3-Dihydro-1H-inden-1-yl)-2,2,2-trifluoro-acetamide
CAS号:	155666-94-7
分子式:	C₁₁H₁₀F₃NO
分子量:	229.2
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(-)-N-Trifluoroacetyl-1-aminoindan is an intermediate in the synthesis of (3R)-2,3-Dihydro-3-(2-propyn-1-ylamino)-1H-inden-1-one (D449765), which is a building block in the preparation of Rasagiline (R126000), which is a selective irreversible MAO-B inhibitor. Rasagiline is also an Antiparkinsonian agent.
参考文献	Rabey, J.M., et al.: Clin. Neuropharmacol., 23, 324 (2000); Glezer, S., et al.: Eur. J. Pharmacol., 472, 173 (2003); Youdim, M.B.H., et al.: Biochem. Pharmacol., 66, 1635 (2003); Chen, J.J., et al.: J. Clin. Pharmacol., 45, 878 (2005)